3DM Inc. to Demonstrate Next Generation Nanobiomaterials at

2006 Society For Biomaterials Annual Meeting & Regenerate World Congress

Cambridge , Mass. – 15 March, 2005 – 3DM Inc. President, Zen Chu, has been invited to address the audiences of two leading biomaterials and regenerative medicine conferences. Mr. Chu will present a talk entitled "Entrepreneurship and Prioritizing Opportunities in Biomaterials and Regenerative Medicine" to a combined audience from both conferences, being hosted by the Pittsburgh Tissue Engineering Initiative (PTEI) simultaneously next month in Pittsburgh, Pennsylvania. The presentation will also be followed by a related panel discussion featuring a distinguished panel of biomaterials entrepreneurs, scientists and venture capital investors. The event will take place on Thursday, April 27, 2006 from 3:45-5:45pm at the David Lawrence Convention Center in the heart of Pittsburgh.

"The conference organizers invited 3DM to embody an example of next generation technologies which are having commercial success," said Shuguang Zhang, inventor of the company's technology. "3DM's nanobiomaterials repesent a family of synthetic materials which offer superior functionality and biocompatibility due to their biomimetic design and engineering."

"The conferences' renowned academic leadership -- including Drs. Buddy Ratner, Anthony Atala, Alan Russell, Antonios Mikos, Jeffrey Hubbell, Joseph Vacanti and Robert Nerem -- deserve applause for including this session on commercializing these technologies. Establishing a framework for careful prioritization of both research and commercial opportunities is the best way to focus the efforts of the life science community toward real clinical therapies," emphasized Mr. Chu.

Mr. Chu's presentation will also cite recent peer-reviewed research demonstrating 3DM's technologies in the following areas:

Cardiac Regeneration: Hsieh PC, Davis ME, Gannon J, MacGillivray C, Lee RT. Controlled delivery of PDGF-BB for myocardial protection using injectable self-assembling peptide nanofibers. J Clin Invest. 116(1):237-48 (2006).

Angiogenesis & Cardiac Tissue Engineering: Narmoneva, D., Oni, O., Sieminski, AL, Zhang, S., Gertler, JP, Kamm, RD, Lee, RT Self-assembling short oligopeptides and the promotion of Angiogenesis. Biomaterials 26: 4837–4846 (2005).

Stem Cells for Cartilage Tissue Engineering: Mauck RL, Helm JM, Tuan RS.  Enhanced Chondrogenesis and Development of Mechanical Properties of Human Mesenchymal Stem Cells Seeded in a Self-Assembling Peptide Hydrogel.  Summer Bioengineering Conference, Vail, CO. (2005).

CNS Regeneration: Ellis-Behnke RG, Liang YX, You SW, Tay DK, Zhang S, So KF, Schneider GE. Nano neuro knitting: peptide nanofiber scaffold for brain repair and axon regeneration with functional return of vision. PNAS 103(13):5054-9 (2006).

About PuraMatrix
PuraMatrix Synthetic Peptide Hydrogels are the best-selling synthetic scaffolds for cell culture and bioproduction research, and have won numerous scientific awards. PuraMatrix gels consist of smart polymers, self-assembling in cell culture or in vivo to create biocompatible nanofiber scaffolds to facilitate healthy cell growth and tissue regeneration. PuraMatrix is currently in pre-clinical testing for orthopedics, cardiac and other medical device and drug delivery applications. PuraMatrix is used by most of the leading pharmaceutical, biotechnology and academic laboratories and has been featured in over thirty premier scientific journal publications. R&D Magazine recently awarded PuraMatrix its 42nd annual R&D 100 Prize as one of the most significant new products to impact life science and medical research.

About 3DM Inc.
3DM is a privately-held specialty biomaterials and medical device company headquartered in Cambridge, Massachusetts. 3DM has partnered with BD Biosciences for marketing PuraMatrix worldwide to the life science research and drug discovery communities. 3DM is further developing their self-assembling peptide hydrogels as medical devices in orthopedics, cardiovascular therapies and drug delivery applications. The patented technology, exclusively licensed from Massachusetts Institute of Technology, was pioneered at MIT through the work and expertise of Drs. Shuguang Zhang, Alan Grodzinsky, Robert Langer, Alexander Rich, Carlos Semino and Lisa Spirio.

Source: 3DM Inc.
               puramatrix.com

Contact: Zen Chu , President
                877-430-9595 contact@puramatrix.com