PuraMatrix® PuraStat®

PuraMatrix® is an ideal synthetic, transparent, biocompatible, and bioresorbable material situated at the intersection of chemical engineering and biology.

PuraMatrix® in vivo extracellular matrix has wide-ranging laboratory and clinical applications, including cell culture, drug delivery, accelerated cartilage and bone growth, and regeneration of CNS, soft tissue, and cardiac muscle.



PuraMatrix® is a fully synthetic, resorbable hydrogel composed of repeating amino acid sequences of Arginine-Alanine-Aspartic Acid-Alanine prepared in an aqueous solution. PuraMatrix® self-assembles into nanofibers on a scale similar to the extracellular matrix when exposed to physiological levels of salt, forming a flowable hydrogel—users can decide exactly when to gel PuraMatrix®. PuraMatrix® nanofibers create a highly organized, 3-dimensional, porous scaffold that is very difficult, if not impossible, to produce by any manufacturing techniques. Additionally, the nanofiber density and average pore size (5-200 nm) can be controlled and customized by the concentration of peptide solution used in production.


PuraMatrix® peptides are produced by well-characterized F-MOC solid-phase peptide synthesis methodology with proprietary processing modifications. The peptide is fill-finished via proprietary aseptic fill-finish and quality testing steps: formulation in liquid, sterile filtration, specification and adjustment of concentration, aseptic fill into vials or syringes, packaging, validation and documentation. Certification of fill-finish manufacturer includes ISO 90001:2000 and ISO 13485.


PuraMatrix® has been tested across multiple standard animal models and in multiple tissue compartments (bone, cartilage, muscle, CNS, intracutaneous injections) – without a single negative safety outcome. This quality is due to PuraMatrix®’s low concentration of fully synthetic, short-length peptides composed of only three standard amino acids forming a biocompatible, biomimetic and bioresorbable nanofiber network structure.


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This website is not intended for French healthcare professionals.

If you are a French healthcare professional, please contact your sales representative for any information.

Ce site internet n’est pas destiné aux professionnels de santé française.

Si vous êtes un professionnel de santé français, merci de contacter votre contact local pour toutes demandes d’informations.