Clinical Applications

PuraMatrix® has demonstrated efficacy in multiple models for hemostasis (CE Mark approved, trade name PuraStat®), tissue regeneration, acute myocardial infarction, therapeutic protein and stem cell delivery, and CNS injury. PuraMatrix® can re-hydrate and provide mechanical support for disc height collapse in degenerated IVDs, anti-adhesion, polyp resection, and bone formation. PuraMatrix® has also been used to repair and restore visual function in the CNS after damage.


Bone and Cartilage Regeneration

PuraMatrix® is an injectable, flowable bone regeneration scaffold. There are numerous opportunities for which PuraMatrix® may be used in combination with many commercially-available orthopedic medical devices and/or products:

  • Orthobiologics: bone graft substitutes, allograft distribution/processing, autogenous bone and soft tissue replacement products and viscoelastics, bone growth stimulators
  • Spinal implants/instrumentation: internal fixation devices, discectomy and vertebroplasty/kyphoplasty products
  • Orthopedic and dental implants
  • Reconstructive surgery: hip, knee, shoulder, elbow, wrist, ankle, and digit implants
  • Fracture fixation: internal fixation and external fixation products
  • Arthroscopy/soft tissue repair: scopes, cameras, instruments, soft tissue implants and repair kits

Click here for peer-reviewed publications of PuraMatrix® in Bone and Cartilage Regeneration clinical applications.


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This website is not intended for French healthcare professionals.

If you are a French healthcare professional, please contact your sales representative for any information.

Ce site internet n’est pas destiné aux professionnels de santé française.

Si vous êtes un professionnel de santé français, merci de contacter votre contact local pour toutes demandes d’informations.