Clinical Applications

PuraMatrix® has demonstrated efficacy in multiple models for hemostasis (CE Mark approved, trade name PuraStat®), tissue regeneration, acute myocardial infarction, therapeutic protein and stem cell delivery, and CNS injury. PuraMatrix® can re-hydrate and provide mechanical support for disc height collapse in degenerated IVDs, anti-adhesion, polyp resection, and bone formation. PuraMatrix® has also been used to repair and restore visual function in the CNS after damage.



PuraMatrix® mechanical barrier formation can also serve as an anti-adhesive. The extracellular matrix formed by application of PuraMatrix® displaces the physical interface between tissues and between tissues and devices, disrupting connectivity. PuraMatrix® anti-adhesive has broad clinical application, including obstetrics, gynecology, and surgery (spine, cardio, and gastrointestinal).

Click here for peer-reviewed publications of PuraMatrix® in clinical applications.


Find out the most recent developments at 3-D Matrix

Learn More


Learn how PuraMatrix® can enhance your technology

Learn More


Review the strong body of literature utilizing PuraMatrix®

Learn More