Laboratory Solutions

PuraMatrix® is the first commercial synthetic extracellular matrix (ECM) scaffold, enabling cells to be cultured in carefully controlled microenvironments for life science research, pharmaceutical drug discovery and bioproduction. PuraMatrix® enhances valuable and expensive cell assays that predict proper drug interactions and metabolism. In particular, PuraMatrix® has improved cell assays in which one or more types of cells form complex structures (such as spheroids, networks, synapses, vascularization). The result is improved models for in vivo and in vitro research and testing, increasing predictability and reducing the cost of drug discovery research. Click here to review PuraMatrix® Guidelines for Use.

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Applications

PuraMatrix® is well suited to meet all cell culture needs. As a 3-dimensional extracellular matrix, PuraMatrix® simulates in vivo growth environments forin vitro investigations. Publications utilizing PuraMatrix® for cell culture in cell based assays report on the following uses among others:

  • Hepatocyte toxicity, induction and metabolism assays
  • Stem cell proliferation and differentiation assays
  • Tumor cell migration and invasion
  • Angiogenesis assays
  • Cardiomyocyte cell culture and in vivo delivery
  • Neurite outgrowth assays
  • Co-culture of various cell types
  • Osteoblast bone growth
  • Chondrocyte and cartilage culture
  • Endothelial, neural, osteoblast 3-D cell structure formation
  • Tissue models for in vitro drug screening
  • Tissue engineering research
  • Bioproduction using PuraMatrix® microcarriers in suspension culture
  • In vivo analyses of tissue regeneration

News

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Collaborations

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Publications

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This website is not intended for French healthcare professionals.

If you are a French healthcare professional, please contact your sales representative for any information.


Ce site internet n’est pas destiné aux professionnels de santé française.

Si vous êtes un professionnel de santé français, merci de contacter votre contact local pour toutes demandes d’informations.

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